[D] Physicist-turned-ML-engineer looking to get into ML research. What's worth working on and where can I contribute most?

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After years of focus on building products, I'm carving out time to do independent research again and trying to find the right direction. I have stayed reasonably up-to-date regarding major developments of the past years (reading books, papers, etc) ... but I definitely don't have a full understanding of today's research landscape. Could really use the help of you experts :-) A bit more about myself: PhD in string theory/theoretical physics (Oxford), then quant finance, then built and sold an ...